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How Beta 1,3-D Glucan Works

Mechanism of Action in the Body

Purification exposes biologically active Beta Glucan layer of Baker’s yeast cell, removing mannoprotein layers, lipids, proteins, nucleic acids and cellular contents. What remains is a hollow microsphere of pure Beta 1,3 Glucan 2-4 microns in diameter.

Baker's Yeast cell is purified to pure Beta 1,3-D Glucan

Beta 1,3-D Glucan works as whole grain particles are biodistributed. Macrophages, a type of white blood that ingests (takes in) foreign material, containing Beta 1,3-D transport it throughout the immune system.

Diagram of human body showing immune system distribution centers

Breakdown of Whole Glucan Particles into soluble Beta Glucan.

stage photos and diagram of glucan particle breakdown

Mechanism of Action

primitive diagram of cellular bonds between pathogen and neutrophil

Two step process. Beta 1,3-D recruits Neutrophils to kill the invading pathogen. Step 1: Macrophages engulf the Beta 1,3-D Glucan via phagocytosis. Step 2: Beta 1,3-D Glucan fragments are secreted and behind to the complement receipt 3 on neutrophils, “priming” them. Neutrophils are white blood cells, specifically a form of granulocyte, filled with neutrally-staining granules, tiny sacs of enzymes that help the cell to kill and digest microorganisms it has engulfed by phagocytosis.

Beta 1,3-D Glucan recruits neutrophils to kill

NOTE: Statements in this document have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.