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Explore the articles below for research information concerning verious topics and conditions in which Beta Glucan 1,3D has been shown to help.

childrenSecretory ImmunityStress


American Journal of immunology 2017 - Richter, J., Stiborová, I., Král, V., Svozil, V., Vetvicka, V., & Rajnohová, D. (3/29/2017). Glucan Supplementation Regulates Secretory Immunity and Stress. American Journal of Immunology, 13(1), 81-85. Retrieved April 15, 2017.  Read More



In our study, we evaluated the effects of short-term supplementation with glucan on NK cells in patients recovering from different types of cancer treatment. NK cells represent a distinct sub-population of lymphocytes endowed with the capacity to kill tumor cells without prior sensitization and form one of the most important defense mechanisms against cancer. To measure the numbers of NK cells, flow cytometer measuring four colors was used. Using a double-blind, placebo-cont rolled clinical trial, we found that adding glucan to the diet strongly incre ased the number of NK cells in blood.  



β-Glucan is a natural immunomodulator consisting of glucose molecules. It is a well-established modifier with significant beneficial properties in infectious diseases and cancer therapy. Glucan effects on melanoma are relatively less studied, despite the increasing incidence of this type of cancer. In the current study, we focused on possible effects of insoluble yeast-derived β-glucan on the growth of melanoma cells. We found that glucan supplementation had a strong-positive effect in both reducing tumor weight, lung colonies and overall survival rate of tested animals. In addition, glucan inhibited the damage to blood cells and potentiated the effects of regular chemotherapy. By using depletion of natural killer (NK) cells, we showed that these effects are, at least partly, mediated by direct action of glucan on NK cells.



Vitamin D and β-glucan supplementation affects levels of leptin, apolipoproteins and general nutrition state in patients with diabetic retinopathy.