Edorium J Pathol 2018 – Vitamin D and β-glucan supplementation affects levels of leptin, apolipoproteins and general nutrition state in patients with diabetic retinopathy.

Glucan also plays an important role in cholesterol regulation, probably via interaction with lipids and biliary salt in the bowel [28]. β-glucan supplementation results in significant risk reduction of atherogenesis and cardiovascular diseases [6, 7, 19, 20]. Also important is the significant weight decrease in Group A patients, which correlated with decrease of leptin (linear regression leptin/BMI is P <0.0014). The fact that leptin plays an important role in homeostatic regulation of energy is well established, and attention is currently focused on its role in glycemia control. These new findings suggest using leptin as supplement in diabetes treatment [15]. Based on our data, we suggest that simultaneous use of β-glucan and vitamin D might be used in complex treatment of diabetic retinopathy [29].  Read more…