Pathology Discovery 2018 – Richter Josef, Závorková Martina, Vetvicka Vaclav*, Král Vlastimil, Stiborova Ivana, Liehneová Ivana and Pohořská Jitka and Rajnohova Dobiasova Lucie. Pathology Discovery, vol. 5, no. 1, 2018, p. 1., doi:10.7243/2052-7896-6-1.  This article again looks at the impact of Beta Glucan when used in conjunction with Vitamin D supplementation on patients identified with Diabetic Retinopathy and Macular Edema, and particularly 7 individuals within that group, who had high levels of IgG4. IgG4 is a subclass of IgG4, which is the most common form of immunoglobulin, which are antibody proteins that are found throughout the body. All 7 individuals were identified through this study to have a probable diagnosis of IgG4ROD (related ophthalmic disease), which involves inflammation, lesions and infiltrates. All the individuals had very low levels of Vitamin D.  The individuals were administered Vitamin D and Transfer Point Beta Glucan over the course of three months.

The study reviewed cited past studies with Vitamin D and Beta Glucan, and came to some strong conclusions: Vitamin D is important to mediate the risk of insulin resistance by its effects on insulin receptors; AND “ Functional food supplemented with glucan represents an important perspective not only for treatment, but also for prevention of diabetes mellitus and additional diseases, and possibly leading to reduce(d) healthcare costs and disease prevalence.” They identified that Glucans have a long history in reducing diabetes and insulitis.

CONCLUSIONS: Long-term evaluation and beta glucan supplementation, combined with vitamin D supplementation, during general treatment of these patients significantly improved both health and mental conditions.
Diabetic Retinopathy is the fifth most common preventable cause of serious vision damage and blindness.  Read more…